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Figure 1 | Cancer Cell International

Figure 1

From: CpG island hypermethylation-associated silencing of microRNAs promotes human endometrial cancer

Figure 1

Epigenetic silencing of miRNAs and EMT-related genes by CpG hypermethylation, and histone modification in endometrial cancer cells. qRT-PCR analysis of miR-130b, miR-301a, and miR-200b expression as well as DICER1, zeb2, CDH1, and vimentin mRNA expression levels in Ishikawa and AN3CA cells treated with 10 μM 5'-aza-CdR and 10 μM TSA. Data were shown as fold change. * P < 0.05, ** P < 0.01, compared to DMSO treatment.

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