Figure 5From: The effects of a histone deacetylase inhibitor on biological behavior of diffuse large B-cell lymphoma cell lines and insights into the underlying mechanismsEffects of TSA on cell cycle arrest and apoptosis proteins in DLBCL cells. (A) Effect of TSA in DoHH2 (50 nM), LY1 and LY8 cells (300 nM) on pAkt and its downstream targets as assessed by western blot. (B) Western blot analysis of apoptosis regulators Bcl-2 and PARP in TSA-treated cells. Arrowhead indicates the cleaved product of PARP. (C) Expression of Bcl-2 in DLBCL cell lines.Back to article page