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Table 4 Clinical response to R-CHOP therapy according to CD20 Exon2 [216] Polymorphism

From: Single nucleotide polymorphisms of CD20 gene and their relationship with clinical efficacy of R-CHOP in patients with diffuse large B cell lymphoma

  Response CD20 exon2[216] genotype n (%) P Value*
  CC No.(%) CT + TT No.(%)
  No.(N = 129) 95 34  
  CR 64(67.4) 16(47.1) 0.091
  PR 22(23.2) 11(32.4)  
  SD/PD 9(9.4) 7(20.5)  
  ORR(CR + PR) 86(90.6) 27(79.5) 0.166#1
  CR 64(67.4) 16(47.1) 0.036#2
  Non-CR 31(32.6) 18(52.9)  
  1. Abbreviations: CR complete response, PR partial response, SD stable disease, PD progressive disease, ORR (OR + PR), overall response, non-CR, PR + SD + PD.
  2. #1 P = 0.166 when comparing ORR with SD/PD;#2 P = 0.036 when comparing CR with non-CR (PR + SD + PD) ;* χ2 test.