Skip to main content

Table 2 Univariate and multivariate analysis of ALDH1A1 phenotype in relation to recurrence-free survival (RFS)

From: Expression of ALDH1 in breast invasive ductal carcinoma: an independent predictor of early tumor relapse

Variable

Univariate analysis

Multivariate analysis

HR

95% CI

P value

HR

95% CI

P value

ALDH1A1

      

 Positive

11.932

4.190–33.977

0.001

11.399

3.776–34.414

0.001

 Negative

1.000

  

1.000

  

ER status

      

 Positive

1.013

0.519–1.977

0.970

1.579

0.636–3.921

0.325

 Negative

1.000

  

1.000

  

PR status

      

 Positive

0.669

0.345–1.299

0.235

0.568

0.238–1.358

0.203

 Negative

1.000

  

1.000

  

HER2 status

      

 Positive

1.307

0.701–2.435

0.400

1.564

0.599–4.085

0.361

Negative

1.000

  

1.000

  

Triple negativity features*

    

 Present

0.848

0.441–1.631

0.620

0.808

0.241–2.702

0.729

 Absent

1.000

  

1.000

  

TNM stage

      

 Stage III/IV

0.718

0.373–1.382

0.321

0.803

0.402–1.601

0.532

 Stage I/II

1.000

  

1.000

  

Age (years)

      

 ≥ 50

0.709

0.376–1.338

0.289

0.803

0.402–1.601

0.532

 < 50

1.000

  

1.000

  
  1. Abbreviations: HR hazard ratio estimated from Cox proportional hazard regression model, CI confidence interval of the estimated HR, ER estrogen receptor, PR progesterone receptor, HER2 human epidermal growth factor receptor 2.
  2. *Immunohistochemically negative for ER, PR, and HER2.
Back to article page

Cancer Cell International

ISSN: 1475-2867

Contact us