Skip to main content

Table 3 Univariate and multivariate analysis of ALDH1A1 phenotype in relation to distant metastasis-free survival (MFS)

From: Expression of ALDH1 in breast invasive ductal carcinoma: an independent predictor of early tumor relapse

Variable

Univariate analysis

Multivariate analysis

HR

95% CI

P value

HR

95% CI

P value

ALDH1A1

      

 Positive

3.501

1.785–6.866

0.001

3.562

1.790–7.091

0.001

 Negative

1.000

  

1.000

  

ER status

      

 Positive

1.111

0.614–2.012

0.727

1.510

0.693–3.290

0.300

 Negative

1.000

  

1.000

  

PR status

      

 Positive

0.956

0.546–1.674

0.875

1.052

0.479–2.310

0.900

 Negative

1.000

  

1.000

  

HER2 status

      

 Positive

0.969

0.554–1.694

0.911

1.161

0. 540–2.495

0.703

 Negative

1.000

  

1.000

  

Triple negativity features*

    

Present

0.870

0.481–1.573

0.645

0.741

0.265–2.073

0.569

 Absent

1.000

  

1.000

  

TNM stage

      

 Stage III / IV

1.874

1.010–3.475

0.046

2.248

1.173–4.307

0.015

 Stage I / II

1.000

  

1.000

  

Age (years)

      

 ≥ 50

1.399

0.793–2.467

0.247

1.585

0.846–2.970

0.151

 < 50

1.000

  

1.000

  
  1. Abbreviations: HR hazard ratio estimated from Cox proportional hazard regression model, CI Confidence interval of estimated HR. ER estrogen receptor, PR progesterone receptor; HER2 human epidermal growth factor receptor 2.
  2. *Immunohistochemically negative for ER, PR, and HER2.
Back to article page

Cancer Cell International

ISSN: 1475-2867

Contact us