The in vivo gene silencing effect of folate-nanoliposome entrapped MYCN siRNA in LA-N-5 neuroblastoma: A, Quantitative RT-PCR analysis of MYCN gene expression. Results are normalized to GAPDH expression and are presented as fold increases over the control. 6 mice each group, *P < 0.05, **P < 0.01; B, Western blot analysis of MYCN gene expression. Frozen tumor samples of each mouse in a same group were mixed and analyzed by Western blot. The right graph is a quantitative analysis of the left one.