Figure 3
From: Localization of BRCA1 protein in breast cancer tissue and cell lines with mutations
BRCA1 protein localization in normal and tumor FFPE sections of poorly differentiated adenocarcinoma (PDA) from patient no. 19. A. H&E section of FFPE normal tissue. B. Consecutive section of the normal tissue stained with the MS110 antibody showed strong epithelial cell nuclear staining. C. Consecutive control section of FFPE tissue without primary antibody. D. H&E section of FFPE tumor tissue. E. Consecutive section of the same tumor treated with pressure cooker antigen retrieval and stained with the MS110 antibody showed that many of the cells exhibit distinct nuclear staining (2). F. Consecutive control section of FFPE tissue without primary antibody. (×200).