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Table 1 Tumor genotype and BRCA1 staining

From: Localization of BRCA1 protein in breast cancer tissue and cell lines with mutations

#Specimen Histology BRCA1 ER/PR Genotype
   FS FFPE   
1. PDA +++ N.A. −/+ N.T.M.
2. MDA ++ +++ +/+ N.T.M.
3. PDA +++ ++ +/+ N.T.M.
4. PDA +++ ++++ −/− BRCA2
6174delT
5. PDA ++++ +++ +/+ N.T.M.
6. MDA ++ ++ +/+ N.T.M.
7. MDA,lob ++ ++ +/+ N.T.M.
8. PDA ++ +++ +/− N.A.
9. Medullary ++ N.A. −/− N.A.
10. Mixed,lob& duct. ++++ ++++ +/− N.T.M.
11. PDA ++ + −/− N.T.M.
12. MDA-PDA ++ ++ +/+ N.T.M.
13. PDA ++ + −/− BRCA1
185delAG
14. MDA-PDA +++ +++ +/+ N.T.M.
15. PDA ++ + +/+ N.T.M.
16. Lobular +++ +++ +/+ N.A.
17. PDA ++ ++ +/− N.A.
18. MDA +++ +++ +/+ N.A.
19. MDA ++ ++ +/− N.A.
20. MDA-PDA ++ ++++ +/+ N.T.M.
21. PDA ++ ++ −/− N.T.M.
22. PDA ++ ++ +/+ N.T.M.
  1. ER/PR= Estrogen/Progesterone Receptor.
  2. MDA= Moderately differentiated adenocarcinoma.
  3. PDA= Poorly differentiated adenocarcinoma.
  4. N.A.= not available.
  5. N.T.M.= no targeted mutations.