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Figure 3 | Cancer Cell International

Figure 3

From: RETRACTED ARTICLE: Diagnosis, classification and grading of canine mammary tumours as a model to study human breast cancer: an Clinico-Cytohistopathological study with environmental factors influencing public health and medicine

Figure 3

Evaluation of accuracy of fine needle aspiration cytology for diagnosis of canine mammary tumours. A: Fine-needle aspirate from a mammary carcinoma in adog. Variation in cell (anisocytosis) and nuclear. (anisokaryosis) size are present, May-Grunwald-Giemsa staining method, 1000X. B: Adenocarcinoma: Malignant mammary epithelial cells: Fine needle aspirate with hypercellular pleomorphic, large hyperchromatic naked cells with coarse and abundant chromatin granules and vacuolar changes, May-Grunwald-Giemsa staining method, 1000X. C: Malignant multinucleated mammary epithelial cell; nuclei exhibit nuclear criteria of malignancy; nuclei superimposed and in different focal planes. May-Grunwald-Giemsa staining method, 1000X. D: Cytological appearance of spindle shape cells, May-Grunwald-Giemsa staining method, 400X. E: Myoepithelial cells (spindle shape) with abundant chromatin granules (red arrows) in adenocarcinoma, May-Grunwald-Giemsa staining method, 1000X. F and G: This cluster of cells shows multinucleated cells containing several irregularly sized nucleiare found in some cases, May-Grunwald-Giemsa staining method, 1000X. H: Fine-needle aspiration biopsy. Benign mammary tumor epithelial cell cluster. Cytological appearance of uniform epithelial cells, May-Grunwald-Giemsa staining method, 400X.

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