Candidate microRNA biomarkers in human epithelial ovarian cancer: systematic review profiling studies and experimental validation

Table 4 The differentially expressed miRNAs (n = 7) with an inconsistent direction between two studies

miRNAs name	Chromosomal localization	Pre-miRNA length	Mature sequence	Direction of expression	Potential target	Reference
miR 494	14q32.31	81 nt	48∣5′-UGAAACAUACACGGGAAACCUC-3′∣69	↑	ARID4B; DZIP3	[11]
				↓		[12]
miR 221	Xp11.3	110 nt	65∣5′-AGCUACAUUGUCUGCUGGGUUUC-3′∣87	↑	LRRCC1; GABRA1	[11]
				↓		[13]
miR 519a	19q13.42	87 nt	54∣5′-AAAGUGCAUCCUUUUAGAGUGU-3′∣75	↑	FILIP1L	[11]
				↓		[7]
miR 335	7q32.2	94 nt	16∣5′-UCAAGAGCAAUAACGAAAAAUGU-3′∣38	↑	SMARCA2; LMX1A	[13]
				↓		[11]
miR 126	9q34.3	85 nt	52∣5′-UCGUACCGUGAGUAAUAAUGCG-3′∣73	↑	HOXA3; PPP3CB	[13]
				↓		[10]
miR 199a	19p13.2	71 nt	6∣5′-CCCAGUGUUCAGACUACCUGUUC-3′∣28	↑	ZNF763	[12]
				↓		[10]
miR 138	16q13	84 nt	10∣5′-AGCUGGUGUUGUGAAUCAGGCCG-3′∣32	↑	PKP4; RIMS2	[14]
				↓		[11]

ISSN: 1475-2867