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Figure 4 | Cancer Cell International

Figure 4

From: SU6668 suppresses proliferation of triple negative breast cancer cells through down-regulating MTDH expression

Figure 4

DNA ploidy of MDA-MB-231 cells treated with SU6668. 001: con group, 002: 15μM group, 003: 30μM group. MDA-MB-231 cells were cultured in media supplemented with SU6668(15μM, 30μM) for 72h, then incubated in PI solution for 30min, detected cell fluorescence intensity, which excitative wavelength was 488nm, and the emissive wavelength was 630nm. After SU6668 treatment, the tetraploid increased in a dose- dependent manner. With the increasing percentage of G2/M phase (tetraploid) cells, the percentage of G1 phase (diploid) cells was reduced.

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