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Figure 10 | Cancer Cell International

Figure 10

From: Low-dose etoposide-treatment induces endoreplication and cell death accompanied by cytoskeletal alterations in A549 cells: Does the response involve senescence? The possible role of vimentin

Figure 10

a-e Progressive changes in the morphology of nuclei in A549 cells after treatment with etoposide - statistical data from microscopic evaluation (staining with DAPI). a Cells with regular nuclei, b cells with nuclei of a regular size and with some morphological abnormalities (lobulation, invaginations, buds), c cells with nuclei indicative of apoptosis (apoptotic bodies), d cells with large nuclei, e cells with features of SAHF formation. Statistically significant differences as compared to the control cells are marked by asterisks (Mann–Whitney U statistics, P<0.05). Columns - median percentage of cells, bars - interquartile range. Results are representative of five independent experiments.

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