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Figure 7 | Cancer Cell International

Figure 7

From: Low-dose etoposide-treatment induces endoreplication and cell death accompanied by cytoskeletal alterations in A549 cells: Does the response involve senescence? The possible role of vimentin

Figure 7

a-f Morphological and ultrastructural changes in A549 cells after treatment with etoposide - electron microscopic examination. a Control cells (x 7 000), b 0.75 μM etoposide (x 5 000), c, d 1.5 μM etoposide (x 4 000), e, f 3 μM etoposide (x 6 000). Progressive alterations in the nucleus and cytoplasm area are evident. At the highest concentration some cells displayed features of extensive lysis/demolition of the cellular content, including dispersed chromatin-like structures appearing in the cytoplasm. Results are representative of five independent experiments.

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Cancer Cell International

ISSN: 1475-2867

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