TY - JOUR AU - Kharmate, Geetanjali AU - Rajput, Padmesh S. AU - Lin, Yu-Chen AU - Kumar, Ujendra PY - 2013 DA - 2013/09/23 TI - Inhibition of tumor promoting signals by activation of SSTR2 and opioid receptors in human breast cancer cells JO - Cancer Cell International SP - 93 VL - 13 IS - 1 AB - Somatostatin receptors (SSTRs) and opioid receptors (ORs) belong to the superfamily of G-protein coupled receptors and function as negative regulators of cell proliferation in breast cancer. In the present study, we determined the changes in SSTR subtype 2 (SSTR2) and μ, δ and κ-ORs expression, signaling cascades and apoptosis in three different breast cancer cells namely MCF-7, MDA-MB231 and T47D. SN - 1475-2867 UR - https://doi.org/10.1186/1475-2867-13-93 DO - 10.1186/1475-2867-13-93 ID - Kharmate2013 ER -