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Table 1 Correlations between VEGF-C and MT1-MMP expression and the clinicopathological features of 106 breast cancers

From: MT1-MMP in breast cancer: induction of VEGF-C correlates with metastasis and poor prognosis

 

VEGF-C expression

MT1-MMP expression

 

Positive

Negative

P

Positive

Negative

P

Tumour

      

  T1

14 (60.9%)

9 (39.1%)

0.023

11 (47.8%)

12 (52.2%)

0.247

  T2

30 (51.7%)

28 (48.3%)

 

23 (39.7%)

35 (60.3%)

 

  T3

7 (41.2%)

10 (58.8%)

 

5 (29.4%)

12 (70.6%)

 

  T4

 

8 (100%)

 

1 (12.5%)

7 (87.5%)

 

N

      

  N0

25 (67.6%)

12 (32.4%)

0.002

23 (62.2%)

14 (37.8%)

<0.001

  N1

21 (45.7%)

25 (54.3%)

 

15 (32.6%)

31 (67.4%)

 

  N2

5 (21.7%)

18 (78.3%)

 

2 (8.7%)

21 (91.3%)

 

Stage

      

  I

7 (77.8%)

2 (22.2%)

0.002

6 (66.7%)

3 (33.3%)

<0.001

  II

39 (54.2%)

33 (45.8%)

 

32 (44.4%)

40 (55.6%)

 

  III

5 (20.0%)

20 (80.0%)

 

2 (8.0%)

23 (92.0%)

 

ER

      

  Positive

21 (35.0%)

39 (65.0%)

0.002

41 (68.3%)

19 (31.7%)

0.1409

  Negative

30 (65.2%)

16 (34.8%)

 

25 (54.3%)

21 (45.7%)

 

PR

      

  Positive

27 (42.2%)

37 (57.8%)

0.132

43 (67.2%)

21 (32.8%)

0.1967

  Negative

24 (57.1%)

18 (42.9%)

 

23 (54.8%)

19 (45.2%)

 

Her2

      

  Positive

24 (42.1%)

33 (57.9%)

0.181

37 (64.9%)

20 (35.1%)

0.5440

  Negative

27 (55.1%)

22 (57.9%)

 

29 (59.2%)

20 (40.8%)

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