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Table 1 Correlations between VEGF-C and MT1-MMP expression and the clinicopathological features of 106 breast cancers

From: MT1-MMP in breast cancer: induction of VEGF-C correlates with metastasis and poor prognosis

  VEGF-C expression MT1-MMP expression
  Positive Negative P Positive Negative P
Tumour       
  T1 14 (60.9%) 9 (39.1%) 0.023 11 (47.8%) 12 (52.2%) 0.247
  T2 30 (51.7%) 28 (48.3%)   23 (39.7%) 35 (60.3%)  
  T3 7 (41.2%) 10 (58.8%)   5 (29.4%) 12 (70.6%)  
  T4   8 (100%)   1 (12.5%) 7 (87.5%)  
N       
  N0 25 (67.6%) 12 (32.4%) 0.002 23 (62.2%) 14 (37.8%) <0.001
  N1 21 (45.7%) 25 (54.3%)   15 (32.6%) 31 (67.4%)  
  N2 5 (21.7%) 18 (78.3%)   2 (8.7%) 21 (91.3%)  
Stage       
  I 7 (77.8%) 2 (22.2%) 0.002 6 (66.7%) 3 (33.3%) <0.001
  II 39 (54.2%) 33 (45.8%)   32 (44.4%) 40 (55.6%)  
  III 5 (20.0%) 20 (80.0%)   2 (8.0%) 23 (92.0%)  
ER       
  Positive 21 (35.0%) 39 (65.0%) 0.002 41 (68.3%) 19 (31.7%) 0.1409
  Negative 30 (65.2%) 16 (34.8%)   25 (54.3%) 21 (45.7%)  
PR       
  Positive 27 (42.2%) 37 (57.8%) 0.132 43 (67.2%) 21 (32.8%) 0.1967
  Negative 24 (57.1%) 18 (42.9%)   23 (54.8%) 19 (45.2%)  
Her2       
  Positive 24 (42.1%) 33 (57.9%) 0.181 37 (64.9%) 20 (35.1%) 0.5440
  Negative 27 (55.1%) 22 (57.9%)   29 (59.2%) 20 (40.8%)  
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