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Table 1 Univariate analysis of overall survival following resection for ICC (n = 81)

From: Prognosis of the intrahepatic cholangiocarcinoma after resection: hepatitis B virus infection and adjuvant chemotherapy are favorable prognosis factors

Clinical factor N Survival rate (%) Median survival (months) P-value (log-rank)
1-year 3-year
Gender      0.608
   Male 48 39.6% 9.2% 10  
   Female 33 48.5% 13.9% 12  
Age      0.108
   ≤ 60 years 43 48.8% 15.2% 12  
   > 60 years 38 36.8% 6.3% 7  
Intrahepatic duct stones      0.277
   Yes 13 53.8% 15.4% 26  
   No 68 41.5% 10.7% 10  
Serum hepatitis index      0.017
   HBsAg or anti-HBc 37 45.9% 15.0% 12  
   anti-HBs + 21 52.4% 16.3% 13  
   All - 23 30.4% 0% 6  
ALT      0.068
   ≤ 40 U/L 45 53.3% 13.2% 13  
   > 40 U/L 36 31.6% 9.8% 10  
CA19-9      0.015
   ≤ 200 U/ml 34 50.0% 19.1% 12  
   > 200 U/ml 47 38.3% 5.1% 8  
GGT      0.008
   ≤ 64 U/L 23 60.9% 19.1% 16  
   > 64 U/L 58 36.2% 7.9% 9  
Total bilirubin      0.124
   ≤ 20 μmol/L 52 48.0% 13.6% 12  
   > 20 μmol/L 29 34.5% 6.9% 9  
Alkaline phosphatase      0.01
   ≤ 119 U/L 30 60.0% 16.2% 15  
   > 119 U/L 51 33.3% 7.8% 8  
Lymphatic metastasis      0.005
   Yes 50 34.0% 6.0% 6  
   No 31 58.1% 20.2% 15  
Operative procedure      0.021
   Radical 60 45.0% 14.2% 12  
   Palliative 21 28.6% 0 5  
Intrahepatic metastasis      0.015
   Yes 31 29.0% 6.5% 6  
   No 50 52.0% 13.9% 13  
Diabetes      0.07
   Yes 6 16.7% 0 5  
   No 75 45.3% 12.0% 12  
Adjuvant chemotherapy      0.001
   Yes 18 83.8% 33.3% 22  
   No 63 31.7% 4.1% 8  
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