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Figure 3 | Cancer Cell International

Figure 3

From: The antiproliferative effect of C2-ceramide on lung cancer cells through apoptosis by inhibiting Akt and NFκB

Figure 3

Treatment with C 2 -ceramide induced different apoptotic profiles in lung cancer H1299 cells. Cells were treated with 0, 10, 20, and 50 μM C2-ceramide for 24 h. (a) Representative apoptotic profiles obtained by Annexin V/PI double staining in C2-ceramide-treated H1299 cells. (b) Quantification analysis results for late apoptosis population (%). Only annexin V (+)/PI (+) regions were analyzed. Data, mean ± SD (n = 3). Asterisks indicate statistically significant differences compared to control (P < 0.001).

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