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Figure 3 | Cancer Cell International

Figure 3

From: Sensitization of U937 leukemia cells to doxorubicin by the MG132 proteasome inhibitor induces an increase in apoptosis by suppressing NF-kappa B and mitochondrial membrane potential loss

Figure 3

Western blot analysis of caspases −3, -8, and −9 and cytochrome c in U937 cells treated with MG132, Doxorubicin (DOX) or MG132 + DOX. U937 cells were cultured and treated with MG132 (1 μM), DOX 1 μM, or with MG132 + DOX. After 24 h, the cells were harvested and lysed. Equivalent amounts of individual lysates were placed onto 10% SDS gradient polyacrylamide gels for electrophoresis and then were electrotransferred onto Immobilon-P PVDF membranes. A representative study is shown. Relative density was calculated using IMAGEJ ver.1.46r software.

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Cancer Cell International

ISSN: 1475-2867

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