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Figure 1 | Cancer Cell International

Figure 1

From: An eEF1A1 truncation encoded by PTI-1 exerts its oncogenic effect inside the nucleus

Figure 1

Schematic overview of the PTI-1 mRNA. The parts with similarity to 23S rRNA and eEF1A1 mRNA are indicated. Upstream AUGs are marked with thin, vertical lines, while the AUG initiating the longest ORF, ORF1, as well as the first three downstream, inframe AUGs are marked with bold, vertical lines. The first positions of the ORF start codons are numbered according to the full-length PTI-1 mRNA (NCBI accession number L41498). The corresponding ORFs are indicated as grey arrows and the calculated molecular weights resulting upon translation of these ORFs are provided to the right of the arrows. The AUG subject to mutation in the different PTI-1-FL-ΔATG constructs is marked with an asterisk.

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