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Table 1 IC 50 values for adriamycin in MCF-7/ADR cells

From: Silencing of ETS1 reverses adriamycin resistance in MCF-7/ADR cells via downregulation of MDR1

Group

IC50(μmol/L)

RR

EST1 siRNA

34.63 ± 1.29*

2.35

Negative control siRNA

86.18 ± 5.29

0.94

Control untransfected

81.37 ± 6.34

1.00

  1. Cytotoxicity was assayed as described in methods. IC50 is the drug concentration (μmol/L) that resulted in a 50% inhibition of cell growth. The RR (relative drug resistance) of the control cells was set as 1. Results are mean ± SD of triplicate determinations; *P < 0.05 compared with the controls.