Figure 1

NPC cell lines had different sensitivities to gefitinib. (A). Gefitinib inhibited the proliferation of NPC cell lines HNE-1 and HK-1 in vitro, as assayed by CCK-8. The IC₅₀ values of HNE-1 and HK-1 for gefitinib were 35 μmol/l and 0.25 μmol/l, respectively. (B). Flow cytometry results showing that 0.25 μmol/l gefitinib significantly increased more apoptosis in HK-1 cells compared with HNE-1 cells (P < 0.05). The results are from three independent experiments and are expressed as mean ± SD.* P < 0.05.