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Figure 6 | Cancer Cell International

Figure 6

From: MiRNA-125a-5p: a regulator and predictor of gefitinib’s effect on nasopharyngeal carcinoma

Figure 6

miR-125a-5p mediated the expression of p53 and Her2 proteins in NPC cells. Western blot analysis confirmed that p53 protein expression was lower in HNE-1 cells than in HK-1 cells. After transfection with oligo-miR-125a-5p mimic, p53 protein expression was increased in HNE-1 cells compared with the control group. Her2 protein expressions were decreased in both cell lines following transfection with oligo-miR-125a-5p mimic in HNE-1 and HK-1 cells. Her2 protein expressions in HK-1 cells were increased after transfection with oligo-miR-125a-5p inhibitor.

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