Table 3 Clinical response to rituximab according to STAT3 polymorphism genotypes
Response | Genotype | p | |
|---|---|---|---|
CC + GG | CG | ||
All patients | |||
CR | 53(60.2) | 34(43.6) | 0.032 |
PR + PD + SD | 35(39.8) | 44(56.4) | |
OR | 77(87.5) | 66(84.6) | 0.591 |
PD + SD | 11(12.5) | 12(15.4) | |
GCB subtype | |||
CR | 14(77.8) | 8(72.7) | 0.758 |
PR + PD + SD | 4(22.2) | 3(27.3) | |
OR | 17(94.4) | 11(100) | 0.426 |
PD + SD | 1(5.6) | 0(0) | |
Non-GCB subtype | |||
CR | 32(57.1) | 19(33.3) | 0.011 |
PR + PD + SD | 24(42.9) | 38(66.7) | |
OR | 46(82.1) | 46(80.7) | 0.844 |
PD + SD | 10(17.9) | 11(19.3) | |