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Table 3 The odds ratio of the best SNP models associated with breast cancer

From: Identifying association model for single-nucleotide polymorphisms of ORAI1 gene for breast cancer

Combined SNP no. (specific SNPs)

SNP Genotypes

Case no./control no.

Cancer (%)

Difference (%)*

Odds ratio (95%CI)

P value

2-SNP (1-4)

2-2

145/101

58.94

7.20

1.357

0.064

 

Others

200/189

51.41

 

(0.983-1.873)

 

3-SNP (1-2-4)

2-1-2

58/31

65.17

6.12

1.689

0.028

 

Others

287/259

52.56

 

(1.058-2.694)

 

4-SNP (1-3-4-5)

2-2-2-1

78/53

59.54

4.33

1.306

0.180

 

others

267/237

52.98

 

(0.884-1.930)

 

5-SNP (1-2-3-4-5)

1-2-3-1-1

14/0

100.00

4.06

13.148

0.013

 

Others

331/290

53.30

 

(1.726-100.142)

 
  1. Bold letters: The SNP models associated with breast cancer are significant (P value < 0.05).
  2. *Difference (%) = Frequency of cases (breast cancer group) - Frequency of controls.
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Cancer Cell International

ISSN: 1475-2867

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