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Table 1 Clinicopathological correlation of PRO2000/ANCCA expression in HCC

From: Significance of PRO2000/ANCCA expression, a novel proliferation-associated protein in hepatocellular carcinoma

Feature Cases PRO2000/ANCCA P-value
- + ++
Gender      0.697
Male 96 38 46 12  
Female 11 3 6 2  
Age (years)      0.524
≤51 53 23 23 7  
>51 54 18 29 7  
Serum HBsAg      0.737
Negative 44 17 20 7  
Positive 63 24 32 7  
Serum AFP (ng/ml)      0.703
≤20 48 18 25 5  
>20 59 23 27 9  
Tumor size (cm)      0.107
≤5 55 25 26 4  
>5 52 16 26 10  
Tumor number      0.003
Single 80 38 32 10  
Multiple 27 3 20 4  
Tumor differentiation      <0.001
I-II 76 40 34 2  
III-IV 31 1 18 12  
Cirrhosis      0.519
Negative 51 21 22 8  
Positive 56 20 30 6  
TNM stage      <0.001
I-II 81 41 38 2  
III-IV 26 0 14 12  
Tumor microsatellite      0.011
Absent 77 36 31 10  
Present 30 5 21 4  
Portal vein tumor thrombus      <0.001
Absent 96 41 47 8  
Present 11 0 5 6  
Recurrence      <0.001
Absent 89 39 43 7  
Present 18 2 9 7  
  1. -, negative; +, moderate positive; ++, strong positive. Significant differences are shown in bold.