TY - JOUR AU - Pharoah, P. D. AU - Dunning, A. M. AU - Ponder, B. A. AU - Easton, D. F. PY - 2004 DA - 2004// TI - Association studies for finding cancer-susceptibility genetic variants JO - Nat Rev Cancer VL - 4 UR - https://doi.org/10.1038/nrc1476 DO - 10.1038/nrc1476 ID - Pharoah2004 ER - TY - JOUR AU - Ruan, K. AU - Song, G. AU - Ouyang, G. PY - 2009 DA - 2009// TI - Role of hypoxia in the hallmarks of human cancer JO - J Cell Biochem VL - 107 UR - https://doi.org/10.1002/jcb.22214 DO - 10.1002/jcb.22214 ID - Ruan2009 ER - TY - JOUR AU - Wang, G. L. AU - Semenza, G. L. PY - 1995 DA - 1995// TI - Purification and characterization of hypoxia-inducible factor 1 JO - J Biol Chem VL - 270 UR - https://doi.org/10.1074/jbc.270.3.1230 DO - 10.1074/jbc.270.3.1230 ID - Wang1995 ER - TY - JOUR AU - Dery, M. A. AU - Michaud, M. D. AU - Richard, D. E. PY - 2005 DA - 2005// TI - Hypoxia-inducible factor 1: regulation by hypoxic and non-hypoxic activators JO - Int J Biochem Cell Biol VL - 37 UR - https://doi.org/10.1016/j.biocel.2004.08.012 DO - 10.1016/j.biocel.2004.08.012 ID - Dery2005 ER - TY - JOUR AU - Wang, G. L. AU - Jiang, B. H. AU - Rue, E. A. AU - Semenza, G. L. PY - 1995 DA - 1995// TI - Hypoxia-inducible factor 1 is a basic-helix-loop-helix-PAS heterodimer regulated by cellular O2 tension JO - Proc Natl Acad Sci U S A VL - 92 UR - https://doi.org/10.1073/pnas.92.12.5510 DO - 10.1073/pnas.92.12.5510 ID - Wang1995 ER - TY - JOUR AU - Frank, B. AU - Hoffmeister, M. AU - Klopp, N. AU - Illig, T. AU - Chang-Claude, J. AU - Brenner, H. PY - 2010 DA - 2010// TI - Single nucleotide polymorphisms in Wnt signaling and cell death pathway genes and susceptibility to colorectal cancer JO - Carcinogenesis VL - 31 UR - https://doi.org/10.1093/carcin/bgq082 DO - 10.1093/carcin/bgq082 ID - Frank2010 ER - TY - JOUR AU - Konac, E. AU - Onen, H. I. AU - Metindir, J. AU - Alp, E. AU - Biri, A. A. AU - Ekmekci, A. PY - 2007 DA - 2007// TI - An investigation of relationships between hypoxia-inducible factor-1 alpha gene polymorphisms and ovarian, cervical and endometrial cancers JO - Cancer Detect Prev VL - 31 UR - https://doi.org/10.1016/j.cdp.2007.01.001 DO - 10.1016/j.cdp.2007.01.001 ID - Konac2007 ER - TY - JOUR AU - Naidu, R. AU - Har, Y. C. AU - Taib, N. A. PY - 2009 DA - 2009// TI - Associations between hypoxia-inducible factor-1alpha (HIF-1alpha) gene polymorphisms and risk of developing breast cancer JO - Neoplasma VL - 56 UR - https://doi.org/10.4149/neo_2009_05_441 DO - 10.4149/neo_2009_05_441 ID - Naidu2009 ER - TY - JOUR AU - Hsiao, P. C. AU - Chen, M. K. AU - Su, S. C. AU - Ueng, K. C. AU - Chen, Y. C. AU - Hsieh, Y. H. AU - Liu, Y. F. AU - Tsai, H. T. AU - Yang, S. F. PY - 2010 DA - 2010// TI - Hypoxia inducible factor-1alpha gene polymorphism G1790A and its interaction with tobacco and alcohol consumptions increase susceptibility to hepatocellular carcinoma JO - J Surg Oncol VL - 102 UR - https://doi.org/10.1002/jso.21539 DO - 10.1002/jso.21539 ID - Hsiao2010 ER - TY - JOUR AU - Kim, Y. H. AU - Park, I. A. AU - Park, W. Y. AU - Kim, J. W. AU - Kim, S. C. AU - Park, N. H. AU - Song, Y. S. AU - Kang, S. B. PY - 2011 DA - 2011// TI - Hypoxia-inducible factor 1alpha polymorphisms and early-stage cervical cancer JO - Int J Gynecol Cancer VL - 21 UR - https://doi.org/10.1097/IGC.0b013e318204f6e6 DO - 10.1097/IGC.0b013e318204f6e6 ID - Kim2011 ER - TY - JOUR AU - Fransen, K. AU - Fenech, M. AU - Fredrikson, M. AU - Dabrosin, C. AU - Soderkvist, P. PY - 2006 DA - 2006// TI - Association between ulcerative growth and hypoxia inducible factor-1alpha polymorphisms in colorectal cancer patients JO - Mol Carcinog VL - 45 UR - https://doi.org/10.1002/mc.20209 DO - 10.1002/mc.20209 ID - Fransen2006 ER - TY - JOUR AU - Tanimoto, K. AU - Yoshiga, K. AU - Eguchi, H. AU - Kaneyasu, M. AU - Ukon, K. AU - Kumazaki, T. AU - Oue, N. AU - Yasui, W. AU - Imai, K. AU - Nakachi, K. AU - Poellinger, L. AU - Nishiyama, M. PY - 2003 DA - 2003// TI - Hypoxia-inducible factor-1alpha polymorphisms associated with enhanced transactivation capacity, implying clinical significance JO - Carcinogenesis VL - 24 UR - https://doi.org/10.1093/carcin/bgg132 DO - 10.1093/carcin/bgg132 ID - Tanimoto2003 ER - TY - JOUR AU - Li, H. AU - Bubley, G. J. AU - Balk, S. P. AU - Gaziano, J. M. AU - Pollak, M. AU - Stampfer, M. J. AU - Ma, J. PY - 2007 DA - 2007// TI - Hypoxia-inducible factor-1alpha (HIF-1alpha) gene polymorphisms, circulating insulin-like growth factor binding protein (IGFBP)-3 levels and prostate cancer JO - Prostate VL - 67 UR - https://doi.org/10.1002/pros.20589 DO - 10.1002/pros.20589 ID - Li2007 ER - TY - JOUR AU - Apaydin, I. AU - Konac, E. AU - Onen, H. I. AU - Akbaba, M. AU - Tekin, E. AU - Ekmekci, A. PY - 2008 DA - 2008// TI - Single nucleotide polymorphisms in the hypoxia-inducible factor-1alpha (HIF-1alpha) gene in human sporadic breast cancer JO - Arch Med Res VL - 39 UR - https://doi.org/10.1016/j.arcmed.2007.11.012 DO - 10.1016/j.arcmed.2007.11.012 ID - Apaydin2008 ER - TY - JOUR AU - Putra, A. C. AU - Tanimoto, K. AU - Arifin, M. AU - Hiyama, K. PY - 2011 DA - 2011// TI - Hypoxia-inducible factor-1alpha polymorphisms are associated with genetic aberrations in lung cancer JO - Respirology VL - 16 UR - https://doi.org/10.1111/j.1440-1843.2011.01972.x DO - 10.1111/j.1440-1843.2011.01972.x ID - Putra2011 ER - TY - JOUR AU - Qin, C. AU - Cao, Q. AU - Ju, X. AU - Wang, M. AU - Meng, X. AU - Zhu, J. AU - Yan, F. AU - Li, P. AU - Ding, Q. AU - Chen, J. AU - Gu, M. AU - Zhang, W. AU - Yin, C. AU - Zhang, Z. PY - 2012 DA - 2012// TI - The polymorphisms in the VHL and HIF1A genes are associated with the prognosis but not the development of renal cell carcinoma JO - Ann Oncol VL - 23 UR - https://doi.org/10.1093/annonc/mdr325 DO - 10.1093/annonc/mdr325 ID - Qin2012 ER - TY - JOUR AU - Ollerenshaw, M. AU - Page, T. AU - Hammonds, J. AU - Demaine, A. PY - 2004 DA - 2004// TI - Polymorphisms in the hypoxia inducible factor-1alpha gene (HIF1A) are associated with the renal cell carcinoma phenotype JO - Cancer Genet Cytogenet VL - 153 UR - https://doi.org/10.1016/j.cancergencyto.2004.01.014 DO - 10.1016/j.cancergencyto.2004.01.014 ID - Ollerenshaw2004 ER - TY - JOUR AU - Ling, T. S. AU - Shi, R. H. AU - Zhang, G. X. AU - Zhu, H. AU - Yu, L. Z. AU - Ding, X. F. PY - 2005 DA - 2005// TI - Common single nucleotide polymorphism of hypoxia-inducible factor-1alpha and its impact on the clinicopathological features of esophageal squamous cell carcinoma JO - Chin J Dig Dis VL - 6 UR - https://doi.org/10.1111/j.1443-9573.2005.00223.x DO - 10.1111/j.1443-9573.2005.00223.x ID - Ling2005 ER - TY - JOUR AU - Orr-Urtreger, A. AU - Bar-Shira, A. AU - Matzkin, H. AU - Mabjeesh, N. J. PY - 2007 DA - 2007// TI - The homozygous P582S mutation in the oxygen-dependent degradation domain of HIF-1 alpha is associated with increased risk for prostate cancer JO - Prostate VL - 67 UR - https://doi.org/10.1002/pros.20433 DO - 10.1002/pros.20433 ID - Orr-Urtreger2007 ER - TY - JOUR AU - Hu, X. AU - Lin, S. AU - Zheng, J. AU - Guo, R. AU - Li, H. AU - You, C. PY - 2013 DA - 2013// TI - Clinicopathological significance of hypoxia-inducible factor-1 alpha polymorphisms in cancers: evidence from a meta-analysis JO - Tumour Biol VL - 34 UR - https://doi.org/10.1007/s13277-013-0971-0 DO - 10.1007/s13277-013-0971-0 ID - Hu2013 ER - TY - JOUR AU - Zintzaras, E. AU - Lau, J. PY - 2008 DA - 2008// TI - Synthesis of genetic association studies for pertinent gene-disease associations requires appropriate methodological and statistical approaches JO - J Clin Epidemiol VL - 61 UR - https://doi.org/10.1016/j.jclinepi.2007.12.011 DO - 10.1016/j.jclinepi.2007.12.011 ID - Zintzaras2008 ER - TY - JOUR AU - Shieh, T. M. AU - Chang, K. W. AU - Tu, H. F. AU - Shih, Y. H. AU - Ko, S. Y. AU - Chen, Y. C. AU - Liu, C. J. PY - 2010 DA - 2010// TI - Association between the polymorphisms in exon 12 of hypoxia-inducible factor-1alpha and the clinicopathological features of oral squamous cell carcinoma JO - Oral Oncol VL - 46 UR - https://doi.org/10.1016/j.oraloncology.2010.04.009 DO - 10.1016/j.oraloncology.2010.04.009 ID - Shieh2010 ER - TY - JOUR AU - Wang, X. AU - Liu, Y. AU - Ren, H. AU - Yuan, Z. AU - Li, S. AU - Sheng, J. AU - Zhao, T. AU - Chen, Y. AU - Liu, F. AU - Wang, F. AU - Huang, H. AU - Hao, J. PY - 2011 DA - 2011// TI - Polymorphisms in the hypoxia-inducible factor-1alpha gene confer susceptibility to pancreatic cancer JO - Cancer Biol Ther VL - 12 UR - https://doi.org/10.4161/cbt.12.5.15982 DO - 10.4161/cbt.12.5.15982 ID - Wang2011 ER - TY - JOUR AU - Mera-Menendez, F. AU - Hinojar-Gutierrez, A. AU - Guijarro, R. M. AU - de Gregorio, J. G. AU - Mera-Menéndez, E. AU - Sánchez, J. J. AU - Quintanilla, M. AU - Cerezo, L. AU - Gamallo, C. PY - 2013 DA - 2013// TI - Polymorphisms in HIF-1alpha affect presence of lymph node metastasis and can influence tumor size in squamous-cell carcinoma of the glottic larynx JO - Clin Transl Oncol VL - 15 UR - https://doi.org/10.1007/s12094-012-0930-z DO - 10.1007/s12094-012-0930-z ID - Mera-Menendez2013 ER - TY - JOUR AU - Min, J. H. AU - Yang, H. AU - Ivan, M. AU - Gertler, F. AU - Kaelin, W. G. AU - Pavletich, N. P. PY - 2002 DA - 2002// TI - Structure of an HIF-1alpha -pVHL complex: hydroxyproline recognition in signaling JO - Science VL - 296 UR - https://doi.org/10.1126/science.1073440 DO - 10.1126/science.1073440 ID - Min2002 ER - TY - JOUR AU - Munoz-Guerra, M. F. AU - Fernandez-Contreras, M. E. AU - Moreno, A. L. AU - Martin, I. D. AU - Herraez, B. AU - Gamallo, C. PY - 2009 DA - 2009// TI - Polymorphisms in the hypoxia inducible factor 1-alpha and the impact on the prognosis of early stages of oral cancer JO - Ann Surg Oncol VL - 16 UR - https://doi.org/10.1245/s10434-009-0503-8 DO - 10.1245/s10434-009-0503-8 ID - Munoz-Guerra2009 ER - TY - JOUR AU - Agundez, J. A. PY - 2008 DA - 2008// TI - Polymorphisms of human N-acetyltransferases and cancer risk JO - Curr Drug Metab VL - 9 UR - https://doi.org/10.2174/138920008784892083 DO - 10.2174/138920008784892083 ID - Agundez2008 ER - TY - JOUR AU - Spinola, M. AU - Conti, B. AU - Ravagnani, F. AU - Fabbri, A. AU - Incarbone, M. AU - Cataldo, I. AU - Pira, E. AU - Pelucchi, C. AU - La Vecchia, C. AU - Dragani, T. A. PY - 2004 DA - 2004// TI - A new polymorphism (Ser362Thr) of the L-myc gene is not associated with lung adenocarcinoma risk and prognosis JO - Eur J Cancer Prev VL - 13 UR - https://doi.org/10.1097/00008469-200402000-00014 DO - 10.1097/00008469-200402000-00014 ID - Spinola2004 ER - TY - JOUR AU - Shivamallappa, S. M. AU - Venkatraman, N. T. AU - Shreedhar, B. AU - Mohanty, L. AU - Shenoy, S. PY - 2011 DA - 2011// TI - Role of angiogenesis in oral squamous cell carcinoma development and metastasis: an immunohistochemical study JO - Int J Oral Sci VL - 3 UR - https://doi.org/10.4248/IJOS11077 DO - 10.4248/IJOS11077 ID - Shivamallappa2011 ER - TY - JOUR AU - Hanahan, D. AU - Weinberg, R. A. PY - 2011 DA - 2011// TI - Hallmarks of cancer: the next generation JO - Cell VL - 144 UR - https://doi.org/10.1016/j.cell.2011.02.013 DO - 10.1016/j.cell.2011.02.013 ID - Hanahan2011 ER - TY - JOUR AU - Ribeiro, A. L. AU - Correia, J. AU - Ribeiro, V. PY - 2009 DA - 2009// TI - Ethnic variability of HIF-1alpha polymorphisms JO - Cancer Biomark VL - 5 ID - Ribeiro2009 ER - TY - JOUR AU - Schaid, D. J. AU - Jacobsen, S. J. PY - 1999 DA - 1999// TI - Biased tests of association: comparisons of allele frequencies when departing from Hardy-Weinberg proportions JO - Am J Epidemiol VL - 149 UR - https://doi.org/10.1093/oxfordjournals.aje.a009878 DO - 10.1093/oxfordjournals.aje.a009878 ID - Schaid1999 ER - TY - JOUR AU - Gao, Y. AU - Xiao, Q. AU - Ma, H. AU - Li, L. AU - Liu, J. AU - Feng, Y. AU - Fang, Z. AU - Wu, J. AU - Han, X. AU - Zhang, J. AU - Sun, Y. AU - Wu, G. AU - Padera, R. AU - Chen, H. AU - Wong, K. K. AU - Ge, G. AU - Ji, H. PY - 2010 DA - 2010// TI - LKB1 inhibits lung cancer progression through lysyl oxidase and extracellular matrix remodeling JO - Proc Natl Acad Sci U S A VL - 107 UR - https://doi.org/10.1073/pnas.1004952107 DO - 10.1073/pnas.1004952107 ID - Gao2010 ER - TY - JOUR AU - Teicher, B. A. AU - Fricker, S. P. PY - 2010 DA - 2010// TI - CXCL12 (SDF-1)/CXCR4 pathway in cancer JO - Clin Cancer Res VL - 16 UR - https://doi.org/10.1158/1078-0432.CCR-09-2329 DO - 10.1158/1078-0432.CCR-09-2329 ID - Teicher2010 ER - TY - JOUR AU - Knechtel, G. AU - Szkandera, J. AU - Stotz, M. AU - Hofmann, G. AU - Langsenlehner, U. AU - Krippl, P. AU - Samonigg, H. AU - Renner, W. AU - Langner, C. AU - Dehchamani, D. AU - Gerger, A. PY - 2010 DA - 2010// TI - Single nucleotide polymorphisms in the hypoxia-inducible factor-1 gene and colorectal cancer risk JO - Mol Carcinog VL - 49 ID - Knechtel2010 ER -