miR-639 promotes the proliferation and invasion of breast cancer cell in vitro

Table 1 Associtions between miR-639 and clinical parameters (n = 158)

Characteristic	No. of patients		*miR-639 ΔCt* ^a	P
	No.	%	Mean ± SD
Age, years
≥60	69	43.7	1.71 ± 0.17	0.664
<60	89	56.3	1.64 ± 0.21
Pathologe grade
I	56	35.4	1.69 ± 0.21
II	49	31.0	1.86 ± 0.14	0.089
III	53	33.5	1.98 ± 0.15
T stage
T1	57	36.1	1.54 ± 0.27	0.471
T2	50	31.6	1.65 ± 0.24
T3	51	32.3	1.33 ± 0.17
M stage
M0	76	48.1	1.19 ± 0.14	0.024
M1	82	51.9	2.11 ± 0.31
Histologic signs of severity (vascular emboli, perineural invasion, diffuse infiltration)
None	77	48.7	1.57 ± 0.23	0.038
Presence	74	46.8	1.73 ± 0.17
Missing	7	4.4
Smoking history
Nonsmoker	111	70.3	1.37 ± 0.23	0.625
Smoker	39	24.7	1.47 ± 0.21
Missing	8	5.1
Alcohol history
Nondrinker	107	67.7	1.35 ± 0.29	0.225
Drinker	42	26.6	1.27 ± 0.36
Missing	9	5.7

Abbreviations: SD standard deviation, T tumor stage, N lymphnode stage.
^aΔCt indicates the difference in the cycle number at which a sample’s fluorescent signal passes a given threshold above baseline (Ct) derived from a specific gene compared with that of U6 in tumor tissues.

ISSN: 1475-2867