Figure 1From: Microvessel area as a predictor of sorafenib response in metastatic renal cell carcinomaHigh (panel A) and low (panel B) microvessel area (MVA) by AQUA. We used a cocktail of anti-cytokeratin and anti-carbonic anhydrase-9 conjugated to Cy2 to create a tumor mask (green), and anti-CD-34 conjugated to Cy5 (red) to identify microvessels. An example of a patient with high MVA is shown in panel A, and an example of low MVA in panel B. The corresponding MVA scores were 28.37% and 3.31%.Back to article page