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Table 2 Associations between markers and response to sorafenib

From: Microvessel area as a predictor of sorafenib response in metastatic renal cell carcinoma

 

Mean +/- STD

   

Marker

Responders

Non-responders

Delta

t-statistic

p-value

MVA

10.3

+/-

9.7

5.6

+/-

4.2

4.7

2.847

0.0055

VEGF

33.4

+/-

11.2

38

+/-

10.9

-4.6

-1.548

0.125

VEGF-R1

32.4

+/-

7.6

33

+/-

8.2

-0.6

-0.288

0.7739

VEGF-R2

31.4

+/-

8.3

33.4

+/-

8.0

-2

-0.929

0.3554

VEGF-R3

48.3

+/-

13.3

50.9

+/-

10.2

-2.6

-0.879

0.3817

c-RAF

35.1

+/-

14.9

34.4

+/-

13.5

0.7

-0.177

0.8601

B-RAF

39.5

+/-

12.8

42

+/-

14.1

-2.5

-0.707

0.4813

c-Kit

44.0

+/-

12.8

43.8

+/-

12.4

0.2

-0.047

0.9629

PDGFR-β

37.5

+/-

14.9

33.6

+/-

9.5

3.9

-1.321

0.1897