Figure 3

Ca²⁺mobilizing agents induced glutamate release in astrocytoma cells. Fluorescence traces representing glutamate release elicited by vehicle (far left) thapsigargin (left), an inhibitor of the endoplasmic reticulum Ca²⁺ ATPase, ionomycin (right), a Ca²⁺ ionophore, and t-ACPD (far right), a selective metabotropic glutamate receptor agonist. The traces are representative for 4–6 independent experiments.