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Figure 3 | Cancer Cell International

Figure 3

From: The ATRA-induced differentiation of medulloblastoma cells is enhanced with LOX/COX inhibitors: an analysis of gene expression

Figure 3

Changes in the expression of the GDF15 gene in Daoy (A) and D283 Med (B) cells analyzed using RT-PCR. The cells were treated with ATRA alone or in combination with CA (an inhibitor of 5-LOX) or CX (an inhibitor of COX-2); numbers indicate the concentrations of these compounds in μM. Respective numerical data from densitometry for three independent experiments are shown in the graphs: X-axis, treatment condition; Y-axis, relative gene expression. The data represent the means ± SD; they were normalized to the expression of the HSP90AB1 housekeeping gene and were related to the untreated control cells. Representative electrophoresis is presented for each cell line.

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