The ATRA-induced differentiation of medulloblastoma cells is enhanced with LOX/COX inhibitors: an analysis of gene expression

Table 2 Genes with changed expression in a particular cell line (Daoy or D283 Med) after combined treatment with ATRA and both inhibitors (CA or CX)

Daoy cell line
Upregulated:	ACP2, *GDF15* , HLA-G, KRT18, MARS, NOTCH2, PPARG, *UBE2L6*
Downregulated:	CD24, COL6A3, FBN1, GAS6, HMGB1, JUND, PLK2, YBX1
D283 Med cell line
Upregulated:	AP2M1, ATF4, BLMH, CANX, CDKN1A, COX6C, COX7A2, FTL, *GDF15* , MAP2K2, PFDN5, PPARD, RARA, RHOA, SOD1, TIMP1, *UBE2L6* , UCHL1
Downregulated:	KPNA2, MYBL2, MYC

The genes that were influenced via the combinations of both inhibitors are typed in bold.

ISSN: 1475-2867