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Table 3 Genes with changed expression detected after the same type of combined treatment (ATRA with CA or ATRA with CX) in both cell lines (Daoy and D283 Med)

From: The ATRA-induced differentiation of medulloblastoma cells is enhanced with LOX/COX inhibitors: an analysis of gene expression

ATRA/CA

 

Upregulated:

GDF15, UBE2L6

Downregulated:

CCND2

ATRA/CX

 

Upregulated:

ATF4, CDKN1A, GDF15 , HMGA1, HMGB1, PFDN5, TIMP1, UBE2L6

Downregulated:

AP2M1

  1. The genes that were influenced via the combinations of both inhibitors are typed in bold.