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Figure 2 | Cancer Cell International

Figure 2

From: Caveolin-1 induces lamellipodia formation via an Akt-dependent pathway

Figure 2

Caveolin-1 increases lung cancer H23 cell migration. (A) Confluent monolayers of Cav-1 transfected (H23/Cav-1), control (H23/Ctrl), shRNA-Cav-1-transfected (H23/shCav-1), and shRNA scrambled (H23/shCtrl) cells were wounded using a 1-mm-wide tip and allowed to migrate for 24 h. The wound space was visualized under a microscope and represented as relative migration level. Data are means ± SD (n = 4). *, p < 0.05 vs. control transfected cells. (B) For transwell assay, cell migration was examined by a transwell assay for 24 h. Migratory cells at the basolateral side of the membrane were stained with Hoechst 33342 for 30 min and visualized under a fluorescence microscope.

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