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Table 2 Expressions of MAPK signal pathway-related proteins and VEGF-C protein after BMPR-II silence in HepG2 cells (RGS, x ± s, n = 3)

From: Effects of siRNA targeting BMPR-II on the biological activities of human liver cancer cells and its mechanism

Group

A

B

C

BMPR-II

0.95 ± 0.02

0.92 ± 0.04

0.46 ± 0.02*

VEGF-C

0.97 ± 0.03

0.82 ± 0.03

0.33 ± 0.05*

p-P38

0.95 ± 0.04

0.86 ± 0.06

0.45 ± 0.05*

p-ERK1/2

0.98 ± 0.05

0.90 ± 0.04

0.35 ± 0.03*

 

0.97 ± 0.03

0.86 ± 0.03

0.32 ± 0.04*

p-JNK

0.93 ± 0.02

0.90 ± 0.03

0.87 ± 0.05

P38

0.97 ± 0.04

0.98 ± 0.05

0.96 ± 0.03

ERK1/2

0.90 ± 0.03

0.96 ± 0.05

0.97 ± 0.05

JNK

0.98 ± 0.05

0.94 ± 0.04

0.96 ± 0.03

  1. Notes: BMPR-II: bone morphogenetic protein receptor II; RGS: relative gray scales; A: normal control group; B: negative control group; C: BMPR-II-siRNA-a group.
  2. *P < 0.01 vs group A and B.
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Cancer Cell International

ISSN: 1475-2867

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