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Table 3 Expressions of MAPK signal pathway-related proteins and VEGF-C protein after BMPR-II silence combined with inhibiting MAPK signal pathway in HepG2 cells (RGS, x ± s, n = 3)

From: Effects of siRNA targeting BMPR-II on the biological activities of human liver cancer cells and its mechanism

 Group

A

B

C

D

p-ERK1/2

0.20 ± 0.04

0.87 ± 0.03

0.88 ± 0.05

0.82 ± 0.03

 

0.36 ± 0.03

0.90 ± 0.03

0.92 ± 0.05

0.91 ± 0.06

p-P38

0.85 ± 0.04

0.34 ± 0.05

0.84 ± 0.05

0.89 ± 0.02

p-JNK

0.87 ± 0.04

0.91 ± 0.02

048 ± 0.02

0.91 ± 0.01

VEGF-C

0.44 ± 0.02 *

0.34 ± 0.02*

0.79 ± 0.01

0.79 ± 0.02

  1. Notes: BMPR-II: bone morphogenetic protein receptor II; RGS: relative gray scales; A: BMPR-II-siRNA-a + PD98059 group; B: BMPR-II-siRNA-a + SB203580 group; C: BMPR-II-siRNA-a + SP600125 group; D: normal control group.
  2. *P < 0.01 vs group C and D. #P < 0.01 vs group A.
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Cancer Cell International

ISSN: 1475-2867

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