Figure 4

Inhibitory effects of enforced Dd-mrp4 expression on the proliferation of several human tumor cell lines. Tumor cell lines (A549, HeLa, HepG2, Caco-2 cells) were seeded in a 6-well plate and transfected with the pcDNA3.1, pcDNA3.1-rps4 (negative control), or pcDNA3.1-mrp4 vector for 6 hrs at 37°C. After 48 hrs of incubation at 37°C, the cell viability was measured as described in Methods. The results represent the mean ± SD in three independent experiments. ns; not significant.