Cancer Cell International

Table 2 Univariate and multivariate analyses of nestin expression in relation to median survival time of ESCC patients

From: Contribution of nestin positive esophageal squamous cancer cells on malignant proliferation, apoptosis, and poor prognosis

Variable	Univariate analysis			Multivariate analysis
Variable	HR	95% CI	*P-value*	HR	95% CI	*P-value*
Nestin expression
Positive	1.579	1.025–2.432	0.038	1.586	1.007–2.499	0.047
Negative	1.000			1.000
Differentiation
Poor	0.680	0.442–1.049	0.081	0.658	0.412–1.053	0.080
Moderate and well	1.000			1.000
TNM classification
III + IV	1.268	0.820–1.961	0.286	0.862	0.201–3.692	0.842
I + II	1.000			1.000
Sex
Male	1.181	0.716–1.946	0.515	1.397	0.826–2.363	0.212
Female	1.000			1.000
Age
≥60 years	0.881	0.582–1.334	0.550	0.755	0.486–1.172	0.210
<60 years	1.000			1.000
Lymph nodes metastasis
With	1.330	0.864–2.048	0.195	1.870	0.451–7.757	0.388
Without	1.000			1.000

Abbreviations: HR hazard ratio; LN lymph nodes.
*Chi-square test.

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