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Figure 4 | Cancer Cell International

Figure 4

From: Metformin inhibition of neuroblastoma cell proliferation is differently modulated by cell differentiation induced by retinoic acid or overexpression of NDM29 non-coding RNA

Figure 4

NDM29 expression level correlates with the differentiation of NB cells toward a neuron-like phenotype. A) SKNBE2-Mock cells expressing the basal level of NDM29 ncRNA; B,C) SKNBE2-S2 and SKNBE2-S1 cells expressing increased level of NDM29 [21]; (scale bar = 50 μm). Upper panels: transmitted light microscopy (EVOS fl, AMG). Lower panels: fluorescence microscopy (Zeiss Axiovert 200 M inverted microscope, Jena Germany). Blue = DAPI, green = GFP (scale bar = 25 μm). D) Real time RT-PCR analysis of NDM29, NF-68, (differentiation markers) and CD29 (adhesion marker) expression.

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Cancer Cell International

ISSN: 1475-2867

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