Figure 4
Effect of isomorellin, forbesione and/or doxorubicin on apoptosis regulated protein expression in CCA cells. A, KKU-M156 cells treated with DMSO or indicated concentrations of doxorubicin or isomorellin or the combination of doxorubicin + isomorellin (C1: 0.007 + 0.06 μM, C2: 0.015 + 0.12 μM, C3: 0.031 + 0.25 μM). B, KKU-100 cells treated with DMSO or indicated concentrations of doxorubicin or forbesione or the combination of doxorubicin + forbesione (C1: 0.006 + 0.25 μM, C2: 0.012 + 0.5 μM, C3: 0.025 + 1 μM) for 48 h. Protein expression was determined by Western blot analysis.