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Table 1 IC 50 values of the caged xanthones and doxorubicin in cholangiocarcinoma cells and Chang cells

From: Synergistic effects of isomorellin and forbesione with doxorubicin on apoptosis induction in human cholangiocarcinoma cell lines

Compounds IC50value (μM)
  KKU-100 KKU-M139 KKU-M156 Chang
Isomorellin 3.34 ± 0.12 2.71 ± 0.10 2.26 ± 0.05 74.19 ± 0.39
Forbesione 3.53 ± 0.05 2.29 ± 0.04 2.63 ± 0.05 13.13 ± 0.57
Doxorubicin 0.06 ± 0.02 3.74 ± 0.08 0.007 ± 0.002 13.65 ± 0.41
  1. Mean ± SE of three independent experiments.