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Table 1 Radiobiological parameters in different groups

From: PTOP and TRF1 help enhance the radio resistance in breast cancer cell

Groupings D0 Dq SF2
MDA-MB-435 s 1.372 ± 0.012 0.413 ± 0.033 0.365 ± 0.008
MDA-MB-435 s R60/2 3.782 ± 0.041* 0.667 ± 0.015* 0.646 ± 0.024*
MDA-MB-435 s R60/6 2.563 ± 0.028* 0.593 ± 0.189* 0.534 ± 0.006*
  1. Data were fit into the single-hit multi-target model, and survival curves of both groups were drawn by Graphpad Prism, the SF2, D0, Dq values were calculated (pD0, Dq, SF2 < 0.05). Data were expressed as the mean ± SD. * p <0.05 were considered significant. D0: mean lethal dose, Dq: quasi-threshold dose, SF: surviving fraction.