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Table 1 The ratio of n-3 to n-6 fatty acids in the microsomal or mitochondrial membranes of liver, colon or tumor in mice fed a diet containing either 5% corn oil (CO) or 3% fish oil concentrate (FOC) and 2% CO with or without 2000 IU/kg Vitamin E for two weeks. Two way ANOVA revealed that consumption of supplemental Vitamin E did not effect the fatty acid composition thus ratios due to dietary fat are shown. Mean ± SEM, (n).

From: Role of lipid peroxidation and antioxidant enzymes in omega 3 fatty acids induced suppression of breast cancer xenograft growth in mice

Tissue Fraction 5% CO 3% FOC/2% COa Fold difference
Liver Microsomal 0.06 ± 0.02 (8) 1.11 ± 0.18 (7) 18.5
  Mitochondrial 0.09 ± 0.02 (8) 0.77 ± 0.08 (7) 8.6
Colon Microsomal 0.18 ± 0.09 (8) 0.62 ± 0.15 (7) 3.4
  Mitochondrial 0.24 ± 0.09 (8) 0.59 ± 0.24 (7) 2.5
Tumor Microsomal 0.11 ± 0.10 (8) 1.15 ± 0.10 (7) 10.5
  Mitochondrial 0.59 ± 0.57 (8) 1.32 ± 0.37 (7) 2.2
  1. a The n-3 to n-6 ratio was significantly higher in every tissue fraction of mice that consumed the FOC diet than in mice that consumed the CO diet.