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Table 2 Activities (mean + SE) of superoxide dismutase (SOD, units/mg protein), catalase (CAT, μmol H2O2decomposed/min/mg protein) and glutathione peroxidase (GPX, μmol β-NADP oxidized/g protein) in the tumors, livers and colon of groups of mice fed diets containing either 5% CO or 3% FOC and 2% CO with or without 2000 IU Vitamin E/kg diet for two weeks.

From: Role of lipid peroxidation and antioxidant enzymes in omega 3 fatty acids induced suppression of breast cancer xenograft growth in mice

Diet type

n

SOD

GPX

CAT

Tumor

5% CO

3

10.0 ± 3.2

131 ± 24a

20 ± 6

5% CO + E

3

17.4 ± 7.2

118 ± 17a

40 ± 17

3% FOC

4

9.0 ± 2.3

60 ± 23a

28 ± 7

3% FOC + E

3

14.1 ± 1.9

13 ± 9b

30 ± 10

Liver

5% CO

3

214 ± 44

358 ± 36

531 ± 28

5% CO + E

3

159 ± 16

301 ± 65

535± 12

3% FOC

4

156 ± 39

308 ± 73

579 ± 22

3% FOC + E

3

87 ± 10

331 ± 96

587 ± 67

Colon

5% CO

3

4.8 ± 0.4

325 ± 59

28 ± 13

5% CO + E

3

11.5 ± 1.5

220 ± 38

35 ± 14

3% FOC

4

2.2 ± 0.6

172 ± 53

21 ± 5

3% FOC + E

3

10.5 ± 3.6

199 ± 42

33 ± 9

  1. a One way ANOVA followed by an SNK multiple comparison test indicated that the mean GPX in the tumors of groups that share a superscript were not significantly different (p < 0.05). There were no other significant differences.