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Table 3 Thiobarbituric acid reactive substances (TBARS, nmols/mg protein, mean ± SE) in the tumors, livers and colons of groups of mice fed diets containing either 5% CO or 3% FOC and 2% CO with or without 2000 IU Vitamin E/kg diet for two weeks. Some mice were sacrificed 24 h after one injection of DOX (5 mg/kg body weight, i.v.).

From: Role of lipid peroxidation and antioxidant enzymes in omega 3 fatty acids induced suppression of breast cancer xenograft growth in mice

Diet type n TBARS before DOX n TBARS after DOX
Tumor
5% CO 4 0.59 ± 0.30cd 3 0.79 ± 0.12cd
5% CO + E 5 0.53 ± 0.05cd 4 0.59 ± 0.21cd
3% FOC 4 1.09 ± 0.14bc 3 1.46 ± 0.29b
3% FOC + E 3 0.38 ± 0.15d 4 2.37 ± 0.37a
Liver
5% CO 4 1.09 ± 0.38b 3 0.98 ± 0.06b
5% CO + E 5 0.69 ± 0.10b 5 0.71 ± 0.09b
3% FOC 4 1.77 ± 0.19a 4 1.99 ± 0.31a
3% FOC + E 3 0.61 ± 0.08b 4 0.60 ± 0.08b
Colon
5% CO 3 2.58 ± 0.47a 3 1.21 ± 0.57a
5% CO + E 4 2.10 ± 1.72a 5 1.00 ± 0.48a
3% FOC 4 3.40 ± 1.13a 4 2.59 ± 1.01a
3% FOC + E 3 2.27 ± 1.22a 5 2.35 ± 0.77a
  1. a,b,c,d One way ANOVA followed by an SNK multiple comparison test indicated that within each tissue type the mean TBARS of each group that share a superscript were not significantly (p < 0.05) different.