Role of lipid peroxidation and antioxidant enzymes in omega 3 fatty acids induced suppression of breast cancer xenograft growth in mice

Table 5 Mean body weight change g/wk ± SE (n) due to diet and to DOX treatment in mice bearing an MDA-MB-231 human breast cancer xenograft.

Diet type	Before DOX treatment Body weight change	After DOX treatment Body weight change
5% CO	0.19 ± 0.15 (15)	-0.42 ± 0.12 (6)
5% CO + E	0.11 ± 0.11 (17)	-0.32 ± 0.08 (8)
3% FOC	0.52 ± 0.06 (23)	-0.32 ± 0.08 (6)
3% FOC + E	0.33 ± 0.06 (22)	-0.40 ± 0.08 (4)
Results of 2-way ANOVA
Fat	S^a	NS
Vit. E	NS	NS
Diet^*Vit. E	NS	NS

^a The tumor bearing mice fed FOC gained significantly more body weight than tumor bearing mice fed CO before DOX treatment. There was no significant difference in body weight loss due to diet in mice given DOX treatment for five weeks.

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