Figure 2From: A phosphorylation defective retinoic acid receptor mutant mimics the effects of retinoic acid on EGFR mediated AP-1 expression and cancer cell proliferationThe phosphorylation defective RARα mutant inhibits proliferation of human cancer cells. Expression of the S77A RARα mutant decreased endogenous RARα phosphorylation in SCC clones (RAR1-4) compared to G418 resistant control cells (neo). RARα protein was immunoprecipitated as described above.Back to article page