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Table 2 Effect of various polylysines on K-562 cell cultures Cell number: × 103 /ml culture medium (average ± SD)

From: Antitumor effect of lysine-isopeptides

Compound SZTP-14 SZTP-15
dose (μg/ml) Control 1 10 100 Control 1 10 100
Hours after treatment 24 120 ± 10 93.3 ± 11 90 ± 20 0 120 ± 15 100 ± 11 60 ± 15 50 ± 15
48 223.3 ± 156.6 ± 5 83.3 ± 5 0 190 ± 11 140 ± 15 120 ± 19 20 ± 5
72 240 ± 17 173.3 ± 136.6 ± 15 0 250 ± 15 190 ± 10 110 ± 25 10 ± 5
Compound SZTP-16 SZTP-17
dose (μg/ml) Control 1 10 100 Control 1 10 100
Hours after treatment 24 130 ± 10 120 ± 13 120 ± 14 120 ± 15 150 ± 15 130 ± 12 120 ± 10 120 ± 10
48 200 ± 15 210 ± 20 160 ± 17 120 ± 10 220 ± 18 210 ± 16 200 ± 17 190 ± 14
72 260 ± 20 280 ± 22 240 ± 23 140 ± 20 280 ± 20 280 ± 18 260 ± 20 210 ± 20
Compound SZTO-18 H-17
dose (μg/ml) Control 1 10 100 Control 1 10 100
Hours after treatment 24 150 ± 14 140 ± 12 120 ± 10 100 ± 11 150 ± 14 120 ± 10 130 ± 11 110 ± 10
48 230 ± 18 210 ± 17 160 ± 15 130 ± 15 230 ± 18 214 ± 14 240 ± 12 210 ± 16
72 280 ± 20 260 ± 22 230 ± 20 180 ± 20 260 ± 22 290 ± 22 280 ± 21 270 ± 20
Compound K-17 A-3
dose (μg/ml) Control 1 10 100 Control 1 10 100
Hours after treatment 24 130 ± 12 120 ± 11 135 ± 11 110 ± 5 120 ± 11 120 ± 10 120 ± 10 12" ± 11
48 200 ± 15 220 ± 15 240 ± 10 210 ± 10 240 ± 14 110 ± 5 110 ± 10 110 ± 5
72 280 ± 17 280 ± 20 290 ± 19 290 ± 19 290 ± 20 110 ± 7 110 ± 5 100 ± 10
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