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Table 1 Densitometric analysis of selected members of the caspase pathway.

From: BRCA1 Zinc RING Finger Domain Disruption Alters Caspase Response in Ovarian Surface Epithelial Cells

  

BRCA1wt

BRCA1+

 

Caspase 3

Procaspase 7

DFF45

Caspase 3

Procaspase 7

DFF45

Control

nd

7.44

21.7

nd

2.9

21.0

0.5 h

nd

5.4

20.52

nd

1.66

14.94

1.0 h

1.4

1.68

8.71

0.61

1.04

3.44

1.5 h

2.4

.35

4.86

2.08

.66

2.06

3.0 h

2.63

nd

nd

3.64

nd

nd

  1. Densitometric analysis of selected members of caspase pathway. Representative immunoblots for activated caspase 3, procaspase 7, and full length DFF45 were scanned and analyzed via the ImagQuant software application. Values reported were normalized to the immunoblots' respective actin levels. An entry of 'nd' represents a value not detectable by the application.
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Cancer Cell International

ISSN: 1475-2867

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