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Table 1 The percent of total fatty acid composition of linoleic acid (LA, n6 18-2), arachidonic acid (AA, n6 20-4), and docosahexaenoic acid (DHA, n3 22-6) in microsomal and in mitochondrial fractions of tumor, of liver and of colon following a two week dietary intervention of AIN·76 food formula without (-) and with (+) supplementation with synthetic vitamin E (2000 IU/kg dry food). Mean ± SD and number of mice (n) are listed.

From: High dietary level of synthetic vitamin E on lipid peroxidation, membrane fatty acid composition and cytotoxicity in breast cancer xenograft and in mouse host tissue

Vitamin E supplement Fraction n LA, 18-2a AA, 20-4 DHA, 22-6b
Tumor      
- Micro 4 8.7 ± 5.0 7.4 ± 12 0.3 ± 0.3
+ " 5 1.9 ± 2.1 7.9 ± 4.2 1.3 ± 1.3
- Mito 4 7.0 ± 5.9 9.6 ± 2.8 0.2 ± 0.5
+ " 5 4.4 ± 5.9 5.8 ± 3.7 2.3 ± 4.9
Liver      
- Micro 4 12.9 ± 5.1 4.9 ± 1.8 1.0 ± 0.9
+ " 5 11.3 ± 1.7 5.4 ± 0.9 1.8 ± 0.3
- Mito 4 14.2 ± 1.5 8.0 ± 0.9 0.5 ± 0.1
+ " 5 12.9 ± 1.2 6.1 ± 1.8 1.4 ± 0.5
Colon      
- Micro 3 5.3 ± 2.1 6.3 ± 2.2 0.3 ± 0.3
+ " 5 4.6 ± 1.2 4.1 ± 1.3 2.4 ± 1.1
- Mito 3 9.4 ± 2.1 2.9 ± 0.2 0.8 ± 0.5
+ " 5 6.3 ± 1.3 3.7 ± 1.6 1.8 ± 1.0
  1. a6 of 6 means lower with vitamin E supplement (p < 0.01 by Fisher's exact test) b6 of 6 means higher with vitamin E supplement (p < 0.01 by Fisher's exact test)